BGC > Produktsuche > Irinotecan EP Impurity E (SN-38) | 86639-52-3

Molecular Formula: C22H20N2O5

Molecular Formula: C22H20N2O5
Molecular Weight: 392.409

Description:
An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. It inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively.

• Molecular Weight:392.40
• Boiling Point:810.3±65.0°C (Predicted)
• Melting Point:>169°C (dec.)
• Purity:≥95%

Molecular Formula:
C22H20N2O5
Canonical SMILES:
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O
InChI:
InChI=1S/C22H20N2O5/c1-3-12-13-7-11(25)5-6-17(13)23-19-14(12)9-24-18(19)8-16-15(20(24)26)10-29-21(27)22(16,28)4-2/h5-8,25,28H,3-4,9-10H2,1-2H3/t22-/m0/s1
InChIKey:
FJHBVJOVLFPMQE-QFIPXVFZSA-N
Solubility:
Soluble in DMSO (Slightly, Sonicated), Methanol (Slightly, Heated, Sonicated)
Appearance:
Pale Yellow to Light Yellow Solid
Application:
the treatment of colorectal cancer
Storage: Store at -20°C
Synonyms:
(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione; 10-Hydroxy-7-ethylcamptothecin; SN 38 Lactone; Irinotecan EP Impurity E; SN-38; USP Irinotecan Related Compound B; Irinotecan Related Compound B; Irinotecan EP Impurity E; NSC-673596

Purity: 98%
Smile code: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CC)C5=CC(O)=CC=C5N=C4C3=C2)=O
MDL Number: MFCD00871873
MolFormula: C22H20N2O5
MolWeight: 392.4046
Available in stock: 797.66

Smile code:
O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CC)C5=CC(O)=CC=C5N=C4C3=C2)=O
MDL Number:
MFCD00871873
Purity :
98%
Available in stock:
726.36 g